"Scientists typically caution, however, that many discoveries in animal models do not translate into therapies for humans." 2010-Aug-30
-- Robert Preidt. (US). Writer for US National Library of Medicine.

2011. 'Many of our major killers reflect the action of a large number of genes with small effects, combined with a major input from the physical and social environment. This work is producing valuable information about some disease processes, but it also emphasises the individuality and variability of the underlying mechanisms of diseases. Clearly, the era of personalised medicine based on our genetic makeup is a long way in the future.' Sir David Weatherall, Lancet 2011;377:1912-13

" There are a thousand subtle ways in which bias can arise, and it's important to make clear that it is not dishonesty. Bias is unconscious and pervasive." Richard Smith, 2006

So, they do research in laboratories and with animals. Although such basic research is unquestionably needed, there is precious little evidence to support this bias towards it. Yet the consequence has been a massive outpouring of laboratory research that has not been properly evaluated to see how relevant it is to patients.' Click for more...

" Knowledge based on Observation of Matters of Fact, is more certain than most Others and in my slender Opinion, less subjected to Mistakes than Reasonings, Hypotheses and Deductions are....." Sir Hans Sloane, 1707

'The concept that animal research, particularly that relating to diet, pharmaceuticals, and environmental agents, may be a poor predictor of human experience is not new.' Click to read more...

'They’re sitting on half a century of data – more than enough to reveal how reliable it really is.' Robert A.J. Matthews, June 2010, BBC Focus Magazine. Click to read more....

'Questions raised about the use of "ALS mice" are prompting a broad reappraisal of the way that drugs are tested in animal models of neurodegenerative disease.' Click for more...

Why animal studies are often poor predictors of human reactions to exposure. Bracken, M B, J R Soc Med 2009 ...click for more